CVS Health has revealed it will shutter 271 additional stores in 2025 as part of its long-term plan to streamline operations and better respond to evolving customer behaviors. This move is a continuation of the pharmacy giant’s enterprise-wide restructuring initiative, which began in 2022 and has already resulted in the closure of nearly 900 stores nationwide.
The announcement was detailed in CVS’s most recent annual report, filed in February, and reflects the company’s broader effort to simplify operations and strengthen its future business model.
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Why Is CVS Closing So Many Locations?
CVS says the store closures are not a response to competitive pressure from industry rivals but a calculated decision informed by data and market shifts. A spokesperson explained that several key factors were considered in the decision-making process:
- Population migration patterns
- Changes in consumer shopping behavior
- Store and pharmacy density in certain areas
- Access to pharmacy care
- Community health needs
The goal, according to CVS, is to optimize the company’s existing footprint by focusing resources on higher-performing locations and improving access to care in underserved communities.
“We’re focused on ensuring we have the right kinds of stores and the right number of stores in the right locations,” a CVS spokesperson said. “Even after these closures, 85% of the U.S. population will still live within 10 miles of a CVS Pharmacy.”
Where Will CVS Be Closing Stores in 2025?
While CVS has not released a full official list of store closures by state, multiple local news outlets and consumer sites like The Krazy Coupon Lady have compiled confirmed locations. So far, at least 34 specific store locations across the country have either closed already in 2025 or are scheduled to close later this year.
Confirmed CVS Closures by State
Alabama
- 2901 Morgan Rd., Bessemer
- 3303 Clairmont Ave., Birmingham
California
- 499 Haight St., San Francisco
- 1701 K St., Sacramento
Florida
- 3090 S. Monroe St., Tallahassee
- 13300 E. Colonial Dr., Orlando
- 2201 Edgewater Dr., Orlando
Georgia
- 439 Highland Blvd., Atlanta
Illinois
- 8639 S. Cicero Ave., Chicago
- 401 W. Armitage Ave., Chicago
- 2000 Skokie Valley Rd., Highland Park
Iowa
- 2420 Lincoln Way, Ames
- 215 Euclid Ave., Des Moines
Massachusetts
- 55 Summer St., Boston
Michigan
- 28774 Gratiot Ave., Roseville
- 27700 Harper Ave., St. Clair Shores
Missouri
- 2435 Independence Ave., Kansas City
- 9433 Manchester Rd., Saint Louis
- 4531 Troost Ave., Kansas City
New York
- 955 Payne Ave., North Tonawanda
- 153 Central Ave., Albany
- 1026 Madison Ave., Albany
- 1241 Lexington Ave., New York
- 1654 Richmond Ave., Staten Island
North Carolina
- 201 W. 4th St., Winston-Salem
Ohio
- 10825 Kinsman Rd., Cleveland
Pennsylvania
- 125 E. Main St., Plymouth
Virginia
- 10390 Willard Way, Fairfax
Washington, D.C.
- 1117 10th St. NW
- 1100 4th St. SW
- 400 Massachusetts Ave. NW
- 1515 New York Ave. NE
- 4500 Wisconsin Ave. NW
- 7828 Georgia Ave. NW
Additional Closures Reported by Local News Outlets
Beyond the initial list, additional store closures have surfaced in media reports from across the U.S., reflecting the broad scope of CVS’s restructuring plan.
Indiana
- 9550 Allisonville Rd., Indianapolis
Maryland
- 1000 S. Charles St., Federal Hill, Baltimore
- 7235 Wisconsin Ave., Bethesda
- 34 N. Cannon Ave., Hagerstown (closing June 26)
Texas
- 3890 Phelan Blvd., Beaumont
What CVS Says About the Strategy
CVS maintains that this realignment is a proactive move to strengthen its business model, not a result of declining performance or mounting industry competition. According to the company, this transformation was set in motion over three years ago and reflects a focus on healthcare delivery innovation, digital solutions, and local market optimization.
Despite reducing its brick-and-mortar footprint, CVS insists that it remains committed to maintaining strong geographic coverage and convenient access to its services.
“Our focus is on health, wellness, and pharmacy care — and our stores are evolving to reflect that,” said the spokesperson.
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Looking Ahead: What This Means for Customers
While store closures can be disruptive for affected communities, CVS says its new strategy will ultimately enhance customer access to health services, especially through digital health platforms and enhanced pharmacy experiences in remaining locations.
Customers in impacted areas are encouraged to transfer prescriptions and seek support from nearby CVS locations or explore the company’s growing telehealth and digital prescription services.
Conclusion
The CVS store closures planned for 2025 are part of a sweeping strategic shift aimed at creating a leaner, more efficient, and more responsive healthcare and retail experience. Although hundreds of communities will see their local CVS shuttered, the company assures customers that most Americans will remain within close proximity to a CVS location — either physically or digitally.